L Citrulline

L-citrulline is a non-essential amino acid that plays a key role in the production of nitric oxide, improving circulation and supporting muscle endurance. Although the body can synthesize it, additional intake through food or supplements can have numerous positive effects on health and physical performance.

Benefits of L-Citrulline

Improves circulation - L-citrulline helps to dilate blood vessels, allowing for better blood flow and supply of oxygen and nutrients to tissues.
Supports heart health - Reduces blood pressure and improves blood vessel function, contributing to cardiovascular health.
Increases physical endurance - Reduces the feeling of fatigue and improves muscle recovery after intense physical activity.
Contributes to detoxification of the body - It is involved in the urea cycle, helping to remove ammonia from the body.
Supports the immune system - Acts as an antioxidant and reduces oxidative stress.

Scientific research on L-citrulline

There are numerous studies investigating the effects of L-citrulline on athletic performance, cardiovascular health, erectile function, and overall physiological support. Here are some key areas of research.

L-citrulline and athletic performance

Studies show that L-citrulline supplementation can reduce fatigue and improve performance in aerobic and anaerobic activities. This is attributed to increased NO production, which improves blood flow and oxygen supply to muscles.
Study (Perez-Guisado & Jakeman, 2010) found that 8g of citrulline malate before training can reduce fatigue and increase the number of repetitions in resistance exercises. "Citrulline malate improves athletic anaerobic performance and alleviates muscle pain" https://pubmed.ncbi.nlm.nih.gov/20386132/
Suzuki et al. (2016) showed that L-citrulline increases ATP levels in muscles, which can improve explosive power and reduce pain after intense exercise.

L-citrulline and cardiovascular health

Research shows that L-citrulline can improve endothelial function and reduce blood pressure in people with hypertension.
Matsumoto et al. (2014) reported that L-citrulline supplementation (6g daily for 4 weeks) lowers systolic and diastolic blood pressure in people with prehypertension.
Breda et al. (2019) investigated the effect of L-citrulline on people with peripheral artery disease and found that it improves blood flow to the extremities.

L-citrulline and erectile function - Alternative to sildenafil citrate (Viagra)

Since it increases NO production, L-citrulline can improve erectile function in men with mild to moderate erectile dysfunction.
A study (Cormio et al., 2011) found that a daily dose of 1.5g of L-citrulline for a month improves erectile function in men with poor circulation.

L-citrulline and ammonia detoxification

As it participates in the urea cycle, L-citrulline helps remove excess ammonia from the body, which can be beneficial for athletes and people with liver disease.
Research (Wagenmakers, 1998) suggests that citrulline can reduce fatigue associated with ammonia accumulation during intense exercise.

Consequences of L-Citrulline Deficiency

L-citrulline deficiency can negatively affect circulation, muscle endurance, and overall health. Some symptoms include:

Poor circulation and feeling of coldness in the extremities
Faster fatigue and longer recovery time after physical activities
Increased risk of high blood pressure and cardiovascular problems
Weakened immune system and greater susceptibility to infections

ProArgi-9+

Meet the power of synergy L-Citrulline, L Arginine, vitamin B6, B12, K2, D3 The most advanced formula for the health of blood vessels and vitality. Revolutionary product of the company Sinergy Worldwide

+385 91 725 4936 Learn more